IgD 抗体 (AA 37-64)
Quick Overview for IgD 抗体 (AA 37-64) (ABIN3031288)
抗原
See all IgD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 37-64
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纯化方法
- Purified
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免疫原
- A portion of amino acids 37-64 from the human protein was used as the immunogen for this IGHD antibody.
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亚型
- IgM
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anti-IgD antibody
适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-IgD (AA 1-240) antibody适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IgD antibody适用: 人 IHC 宿主: 兔 Monoclonal MSVA-701R unconjugated Recombinant Antibody
anti-IgD (AA 1-576) antibody适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-IgD antibody适用: 人 FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal IgD26 unconjugated
anti-IgD antibody适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-IgD antibody (FITC)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 FITC
anti-IgD antibody (iFluor™647)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 iFluor™647
anti-IgD antibody (iFluor™700)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 iFluor™700
anti-IgD antibody (mFluor™450)GMP Grade 适用: 人 FACS 宿主: 小鼠 Monoclonal IA6-2 mFluor™450
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应用备注
- Titration of the IGHD antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IGHD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IgD
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别名
- IGHD
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物质类
- Antibody
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背景
- IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.
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UniProt
- P01880
抗原
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